Klaus P. Hoeflich: search on Z-Library

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1

FRET evidence for a conformational change in TFIIB upon TBP-DNA binding

Le Zheng, Klaus P. Hoeflich, Laura M. Elsby, Mahua Ghosh, Stefan G. E. Roberts, Mitsuhiko Ikura

Journal:

Year:

2004

Language:

english

File:

PDF, 283 KB

english, 2004

2

Erratum: Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers

Hatzivassiliou, Georgia, Haling, Jacob R., Chen, Huifen, Song, Kyung, Price, Steve, Heald, Robert, Hewitt, Joanne F. M., Zak, Mark, Peck, Ariana, Orr, Christine, Merchant, Mark, Hoeflich, Klaus P., Ch

Journal:

Year:

2013

File:

PDF, 27 KB

2013

3

ChemInform Abstract: Glycogen Synthase Kinase-3: Properties, Functions, and Regulation

Adnan Ali, Klaus P. Hoeflich, James R. Woodgett

Journal:

Year:

2001

File:

PDF, 26 KB

2001

4

Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers

Hatzivassiliou, Georgia, Haling, Jacob R., Chen, Huifen, Song, Kyung, Price, Steve, Heald, Robert, Hewitt, Joanne F. M., Zak, Mark, Peck, Ariana, Orr, Christine, Merchant, Mark, Hoeflich, Klaus P., Ch

Journal:

Year:

2013

Language:

english

File:

PDF, 921 KB

english, 2013

5

Calmodulin in Action: Diversity in Target Recognition and Activation Mechanisms

Klaus P. Hoeflich, Mitsuhiko Ikura

Journal:

Year:

2002

Language:

english

File:

PDF, 134 KB

english, 2002

6

Regulation of ERK3/MAPK6 expression by BRAF

Hoeflich, Klaus, Eby, Michael, Forrest, William, Gray, Daniel, Tien, Janet, Stern, Howard, Murray, Lesley, Davis, David, Modrusan, Zora, Seshagiri, Somasekar

Journal:

International Journal of Oncology

Year:

2006

Language:

english

File:

PDF, 531 KB

english, 2006

7

Inhibitors of p21-Activated Kinases (PAKs)

Rudolph, Joachim, Crawford, James J., Hoeflich, Klaus P., Wang, Weiru

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 2.45 MB

english, 2015

8

Combined Targeting of BRAF and CRAF or BRAF and PI3K Effector Pathways Is Required for Efficacy in NRAS Mutant Tumors

Jaiswal, Bijay S., Janakiraman, Vasantharajan, Kljavin, Noelyn M., Eastham-Anderson, Jeffrey, Cupp, James E., Liang, Yuxin, Davis, David P., Hoeflich, Klaus P., Seshagiri, Somasekar, Najbauer, Joseph

Journal:

Year:

2009

Language:

english

File:

PDF, 1.88 MB

english, 2009

9

Systemic Effects by Intrathecal Administration of Triamcinolone Acetonide in Patients With Multiple Sclerosis

Hoeflich, Andreas, Fitzner, Brit, Walz, Christina, Hecker, Michael, Tuchscherer, Armin, Bastian, Manuela, Brenmoehl, Julia, SchrÃ¶der, Ina, Willenberg, Holger S., Reincke, Martin, Zettl, Uwe Klaus

Journal:

Frontiers in Endocrinology

Year:

2020

File:

PDF, 587 KB

2020

10

Structure-Guided Design of Group I Selective p21-Activated Kinase Inhibitors

Crawford, James J., Lee, Wendy, Aliagas, Ignacio, Mathieu, Simon, Hoeflich, Klaus P., Zhou, Wei, Wang, Weiru, Rouge, Lionel, Murray, Lesley, La, Hank, Liu, Ning, Fan, Peter W., Cheong, Jonathan, Heise

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 483 KB

english, 2015

11

Bcl-2 targeted to the endoplasmic reticulum can inhibit apoptosis induced by Myc but not etoposide in Rat-1 fibroblasts

Lee, Si Tuen, Hoeflich, Klaus P, Wasfy, Gihane W, Woodgett, James R, Leber, Brian, Andrews, David W, Hedley, David W, Penn, Linda Z

Journal:

Year:

1999

Language:

english

File:

PDF, 243 KB

english, 1999

12

Glycogen Synthase Kinase-3: Properties, Functions, and Regulation

Ali, Adnan, Hoeflich, Klaus P., Woodgett, James R.

Journal:

Chemical Reviews

Year:

2001

Language:

english

File:

PDF, 179 KB

english, 2001

13

MazF Cleaves Cellular mRNAs Specifically at ACA to Block Protein Synthesis in Escherichia coli

Yonglong Zhang, Junjie Zhang, Klaus P Hoeflich, Mitsuhiko Ikura, Guoliang Qing, Masayori Inouye

Journal:

Year:

2003

Language:

english

File:

PDF, 403 KB

english, 2003

14

pHUSH: a single vector system for conditional gene expression

Daniel C Gray, Klaus P Hoeflich, Li Peng, Zhenyu Gu, Alvin Gogineni, Lesley J Murray, Mike Eby, Noelyn Kljavin, Somasekar Seshagiri, Mary J Cole, David P Davis

Journal:

BMC Biotechnology

Year:

2007

Language:

english

File:

PDF, 1.06 MB

english, 2007

15

p21-Activated kinase inhibitors: a patent review

Crawford, James J, Hoeflich, Klaus P, Rudolph, Joachim

Journal:

Expert Opinion on Therapeutic Patents

Year:

2012

Language:

english

File:

PDF, 842 KB

english, 2012

16

Radixin: cytoskeletal adopter and signaling protein

Klaus P Hoeflich, Mitsuhiko Ikura

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2004

Language:

english

File:

PDF, 173 KB

english, 2004

17

Preclinical disposition and pharmacokinetics-pharmacodynamic modeling of biomarker response and tumour growth inhibition in xenograft mouse models of G-573, a MEK inhibitor

Choo, Edna F., Belvin, Marcia, Chan, Jocelyn, Hoeflich, Klaus, Orr, Christine, Robarge, Kirk, Yang, Xiaoye, Zak, Mark, Boggs, Jason

Journal:

Year:

2010

Language:

english

File:

PDF, 866 KB

english, 2010

18

Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1)

Hoeflich, Klaus P, Yeh, Wen-Chen, Yao, Zhengbin, Mak, Tak W, Woodgett, James R

Journal:

Year:

1999

Language:

english

File:

PDF, 342 KB

english, 1999

19

p21-Activated Kinase 2 Regulates Endothelial Development and Function through the Bmk1/Erk5 Pathway

Radu, Maria, Lyle, Karen, Hoeflich, Klaus P., Villamar-Cruz, Olga, Koeppen, Hartmut, Chernoff, Jonathan

Journal:

Molecular and Cellular Biology

Year:

2015

Language:

english

File:

PDF, 4.63 MB

english, 2015

20

Synthesis and evaluation of a series of 4-azaindole-containing p21-activated kinase-1 inhibitors

Lee, Wendy, Crawford, James J., Aliagas, Ignacio, Murray, Lesley J., Tay, Suzanne, Wang, Weiru, Heise, Christopher E., Hoeflich, Klaus P., La, Hank, Mathieu, Simon, Mintzer, Robert, Ramaswamy, Sreemat

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 2.29 MB

english, 2016

21

FDG-PET is a good biomarker of both early response and acquired resistance in BRAFV600mutant melanomas treated with vemurafenib and the MEK inhibitor GDC-0973

Andreas R Baudy, Taner Dogan, Judith E Flores-Mercado, Klaus P Hoeflich…

Journal:

EJNMMI Research

Year:

2012

Language:

english

File:

PDF, 1.97 MB

english, 2012

22

Insights into a Single Rod-like Helix in Activated Radixin Required for Membrane−Cytoskeletal Cross-Linking †

Hoeflich, Klaus P., Tsukita, Sachiko, Hicks, Leslie, Kay, Cyril M., Tsukita, Shoichiro, Ikura, Mitsuhiko

Journal:

Year:

2003

Language:

english

File:

PDF, 481 KB

english, 2003

23

Targeting cancer with kinase inhibitors

Gross, Stefan, Rahal, Rami, Stransky, Nicolas, Lengauer, Christoph, Hoeflich, Klaus P.

Journal:

Journal of Clinical Investigation

Year:

2015

Language:

english

File:

PDF, 1.19 MB

english, 2015

24

Characterization of Dual Substrate Binding Sites in the Homodimeric Structure of Escherichia coli mRNA Interferase MazF

Guang-Yao Li, Yonglong Zhang, Mitchell C.Y. Chan, Tapas K. Mal, Klaus P. Hoeflich, Masayori Inouye, Mitsuhiko Ikura

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 735 KB

english, 2006

25

Bioanalytical validation for simultaneous quantification of non-aromatic steroids in follicular fluid from cattle via ESI-LC–MS/MS

Kunze, Martin, Wirthgen, Elisa, Walz, Christina, Spitschak, Marion, Brenmoehl, Julia, Vanselow, Jens, Schwerin, Manfred, Wimmers, Klaus, Hoeflich, Andreas

Journal:

Journal of Chromatography B

Year:

2015

Language:

english

File:

PDF, 1.10 MB

english, 2015

26

Role of the E3 ubiquitin ligase RNF157 as a novel downstream effector linking PI3K and MAPK signaling to the cell cycle

Dogan, Taner, Gnad, Florian, Chan, Jocelyn, Phu, Lilian, Young, Amy, Chen, Mark J, Doll, Sophia, Stokes, Matthew P, Belvin, Marcia, Friedman, Lori S, Kirkpatrick, Donald S, Hoeflich, Klaus P, Hatzivas

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 2.25 MB

english, 2017

27

10.1038/35017574

Hoeflich, Klaus P., Luo, Juan, Rubie, Elizabeth A., Tsao, Ming-Sound, Jin, Ou, Woodgett, James R.

Journal:

Year:

2000

Language:

english

File:

PDF, 352 KB

english, 2000

28

[Methods in Enzymology] Small GTPases in Disease, Part B Volume 439 || Inducible BRAF Suppression Models for Melanoma Tumorigenesis

Hoeflich, Klaus P.

Year:

2008

Language:

english

File:

PDF, 395 KB

english, 2008

29

[Cell and Molecular Response to Stress] Protein Adaptations and Signal Transduction Volume 2 || Chapter 13 Mitogen-activated protein kinases and stress

Hoeflich, Klaus P.

Year:

2001

Language:

english

File:

PDF, 1.76 MB

english, 2001

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